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IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Middle Region) Peptid

IKZF1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978461

Kurzübersicht für IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Middle Region) Peptid (ABIN978461)

Target

IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Spezies

Human

Quelle

  • 9
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-IKZF1 antibody (Catalog #: ARP31470_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    Hintergrund

    IKZF1 binds and activates the enhancer (delta-A element) of the CD3-delta gene. It functions in the specification and the maturation of the T-lymphocyte. It also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.

    Alias Symbols: Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1

    Protein Interaction Partner: AP2M1,CHD3,CTBP1,GTF2B,HDAC1,HDAC2,IKZF2,IKZF3,IKZF4,RBBP8,SAP18,SIN3A,SIN3B,SMARCA4,TBP,UBE2I,AP2M1,CHD4,CTBP1,GTF2B,HDAC1,HDAC2,HDAC3,HDAC4,HDAC5,HDAC7,Hdac1,IKZF2,IKZF4,IKZF5,Ikzf3,NCOR2,RBBP8,SIN3A,SIN3B,Sin3a,Sin3b,TBP,UBE2I

    Protein Size: 519

    Molekulargewicht

    57 kDa

    Gen-ID

    10320

    NCBI Accession

    NM_006060, NP_006051

    UniProt

    Q13422
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